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Appendix 12 – HRT Preparations

View HRT Guidance Flow Chart

Table 1: Combined Sequential Hormone Replacement Therapy

Table 2: Estrogen Preparations

Table 3: Progestogen-only Preparations

Although not all of these progestogens are licensed for HRT, they may be tailored to suit individual patients.

Table 4: Period-free therapy

Type Brand Formulation Estrogen Progestogen
Continuous Angeliq Tablets Estradiol (1mg) Drospirenone (2mg)
Climesse Tablets Estradiol Valerate (2mg) Norethisterone (0.7mg)
Combined Elleste Duet Conti Tablets Estradiol (2mg) Norethisterone (1mg)
Kliovance Tablets Estradiol (1mg) Norethisterone (0.5mg)
Therapy Kliofen Tablets Estradiol (2mg) Norethisterone Acetate (1mg)
Premique Tablets Conj. Estrogens (0.625mg) Medroxyprogesterone Acetate (5mg)
Premique Low Dose Tablets Conj. Estrogens (0.3mg) Medroxyprogesterone (1.5mg)
Evorel Conti Patches Estradiol (50µg) Norethisterone Acetate (170µg)
Femseven Conti Patches Estradiol (50µg) Levonorgestrel (10mcg)
Nuvelle Continuous Tablets Estradiol (2mg) Norethisterone Acetate (1mg)
Femoston Conti Tablets Estradiol (1mg) Dydrogesterone (5mg)
Livial Tablets Tibolone (2.5mg) Medroxyprogesterone Acetate (2.5mg)
Indivina Tablets Estradiol Valerate (1mg) Medroxyprogesterone Acetate (5mg)
Tablets Estradiol Valerate (2mg) Medroxyprogesterone (5mg)

Table 5: Vaginal natural estrogen preparations

Brand Formulation Estrogen
Estring Vaginal ring Estradiol (7.5mcg)
Ortho-Gynest Pessary, vaginal cream Estriol (500mcg)
Ovestin Vaginal cream Estriol (0.1%)
Vagifem Vaginal tablet Estradiol (25mcg)

Note: All brand names are the registered trade marks of their respective manufacturers.